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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e78652abbac427e557e3f7d8cc3d7547af83df1504416ef42e511ff681cb9ee' 
  AND token = 'R53L8vusZfAYoxwoO5g71/PHAAuZF+//FxVRDckX2lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}