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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '441de5daf523c9637ead8e7207e87e188d57c2b45e13d9465039bb204ddf644c' 
  AND token = 'ykTlKac8jtInFo4d95OlYlwbIKkHmA+2B5ZDc76aNOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00007

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}