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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50b686308dfc889cc95878575acbffaeb8097635643f1569f1f54f5f0df9e64' 
  AND token = 'IljNhGn7qvz0IWyxOau41qD1rfHQhzszJHuAyIJA/NQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}