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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28cfdf604552e8129a776a6312e71e179f33b2cf5d4fd7cb072669968c56ceea' 
  AND token = 'Ls0xRmwqa3XTVu38UIjP+e06OvH6a55E5NHDjL+6PSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}