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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b7c88cf74cf7f8e73d7cdc95d9f9250c80002d972e8217a406a083f87515692' 
  AND token = 'bOnNkxB4CtIcUBDLQdTQ8JfFJG6JhKwj4I0qGo09Gcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}