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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd722ef6a9f49d757c7e04938c67409d22e461b5d684b40d55ff0318226c8955e' 
  AND token = 'lEHT/xm6xVYeVZmo5NC3CDzXY6P5oHug1YqDfIgP/AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}