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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54fa386658373f373d49e1cb9b7b21c7467ba80e9482963dfab265d35bee1ea7' 
  AND token = 'LJ3D5p2DZ5vsea3MSWPiW3ltWY3JU/OtNj4LlimdiVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}