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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e19a47dfa3b7cbbecefba86b0252b250d099b76d774847042b1017f8bdcba8a' 
  AND token = 'EM3QJbfsaP8j+KCdZ91gE7FYB9w/yyZjP6SiHQ3Cs2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}