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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50171a65db65c27dd585cd2032decebe1efcf0c5e82ae007527a101f14bc92a1' 
  AND token = 'C9WBxtjWQmTNf3ODQDnoCNOtuhaE4kajhFs8NbUI4LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}