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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54895dbbb3c30170d054922954887a350ed40ca5855994601db8d41de4ff1a25' 
  AND token = 'Ko/OWEkNhNPvUjjv0TVhWseea8QAlJeaKFkTiw2VNF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}