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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bcb8e182963119ac61af960a40cc9ef9577f65a123246110732ce9a15b9f72a0' 
  AND token = 'aTTmIRqe96sbEbfyWyi2jPqgWbLr+7wLDDoe5hTp3Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}