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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '006f1dd4d66cf3addc65cbdeaf34f5208cef4f60be8a5e2cdbb4cd98ac265f43' 
  AND token = 'dzlzy7ilAvOVW8GH5S+3ETEqbv0JVN5tdkGqGDjFZEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}