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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd21af8ef8be1f04523955962dc41edb402d5d58a4228c3160c468ad95f141beb' 
  AND token = 'Lg/UPbS8hm1Mfhq6Nnuli5m5wzN0kNZgGA1thUCrZvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}