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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb8138b5d3ef2605fc92d82289bac75114d81f9369a31891f2e66d2110c0511a' 
  AND token = 'YzU8YFiLW+m8Re7apPIL3347zuOvdUGzvMLSWlnp/Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}