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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a40788ae9fed46efaa11f0e7c570cf0025af6f6f3e10643fbd6835c17de47a4' 
  AND token = '4DPQJDnkGV6yCf16lPngUp07h0MMsLDCDZl6D7qJFB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}