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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61cd899bf0b31f3f948efa3fd5c3ca291fcbc4328a8c3ec50700ce9b51276d71' 
  AND token = 'JxQ9DfaR+NWiTUBCyE5U2RzMBSz+VtB9aqQm+4DvqWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}