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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8a5bbcefbe869e54d2dfe5a102efbcfb4f1a8caff1577a47498393de86ed2e7' 
  AND token = '7HmB45L6FT4ha0kqUQ/+JmrPfEaElsfQENh71d4Yuro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}