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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22f206c1a82a1fddeefae92b40b8dd5a759aa06662a164d6cfc050fe56eca2c' 
  AND token = 'HuWZfBvpzRo3rN/qgHqHgj9Ct3+pFuNo7dbK+1JxHQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}