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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8272b90d04f708038e62dae264f3fc5b3df371bcb62b22e17957f718f3ff4ffd' 
  AND token = 'wnsgRYvj38XXK8EDt1LtGgq08u1f9EIjNMwHW8hzxII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}