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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3755a90e1e07517d43b60873a72544a576af4740066db85b43dab1572916f6f8' 
  AND token = 'W+DFVMYkc0Wa2pjpF/HVRNkPSVzZ0rIxaDi8zwpThaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}