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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53525c4def3ab6f4c6b96ab1eeb59bf9d2c8b844ac82f17b952501acfd886a7c' 
  AND token = 'GkpZULlqKC5IHK5z2r1ApP0rFaNtLk4rlvidi8oGlX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}