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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9457d14131e504880beddb13c133dea4b6c84e0ab3d9e3e5c8f46abc69b70165' 
  AND token = 'cfLx/SAEbRZYyEeWsxLlackA6w6anJ7J9S0mZ/qJ3H4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}