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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '182dab43226f54d3b9efac13f7ff196020b5fcbdd4858f6e3af344ad5541a136' 
  AND token = 'lZm8A6rOAzcsvxV6ugi45RdQ6cMMFRy5C8Y1u/9ea5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}