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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd95a10a1f50a63df4cb01c057addbde263b1b9a1da15c7f6a0e3abbc6339f260' 
  AND token = 'oo6AN7/lBZl1DF0fO2/nE/DbVlWlw2AKZWki1ps2c1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}