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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bd18fba8b6ad9d2c0370029e52201b20fa232b10f5fe95ffef4e644182d6846' 
  AND token = 'JuNeMH+5LG/DucQ3WV13xr0Hu/qcKr+qNIqsF3ldmx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}