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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4578f5a8d3a0400445b213f5337b8131c925654865737ab8427bc6509e54db3c' 
  AND token = 'X3j5gxT9zPXx5GTBDX2jp+2iMU+dXijPJlLKodsJs2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}