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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7744e7be5598b524c017af61b5bbba8b7f4d9789bc49e1e4b4b2cdee9cfad57' 
  AND token = 'Mkvuq+gw52glr4VqA6AklbOv7aipJ6/otAbUlW6Tl/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}