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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b0c66250798ae1faedb31cc5c9ef1c7144a324be3e5d3434a5424663d13be8' 
  AND token = 'J2BityO5L/B0j7DOhz1M5odbKMVRoQ/S0r+WeTgMURo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}