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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97ba945524442b7c3d79d6f0fd9439fc461b456df1e3799b78ce0b18a3d79cde' 
  AND token = 'ACkqmj1SQP0p82BdmtSsvDhjGqDQrp7ttcQ5+0Izz8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}