SELECT 
  cscart_product_prices.product_id, 
  MIN(
    IF(
      cscart_product_prices.percentage_discount = 0, 
      cscart_product_prices.price, 
      cscart_product_prices.price - (
        cscart_product_prices.price * cscart_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_product_prices 
WHERE 
  cscart_product_prices.product_id IN (
    2127, 2305, 1812, 2038, 2306, 2129, 2171, 
    2039, 2040, 1985, 2114, 2344, 1949, 
    2041, 2318, 1961, 2042, 1986, 2343, 
    2077, 2172, 2185, 2159, 2216, 2218, 
    2229, 2228, 2186, 2184, 1934, 2358, 
    1994, 2006, 2075, 1962, 2065, 1992, 
    2008, 1984, 1993, 1936, 2238, 2237, 
    2311, 2298, 2043, 1954, 1953, 1752, 
    1827, 1870, 1803, 1828, 1754, 1770, 
    1879, 1874, 1829, 1864, 1904, 1842, 
    1781, 1894, 2153, 1886, 1887, 2085, 
    2195, 2130, 2382, 2011, 1919, 1922, 
    1942, 1923, 1933, 1945, 1946, 2376, 
    1746
  ) 
  AND cscart_product_prices.lower_limit = 1 
  AND cscart_product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  cscart_product_prices.product_id

Query time 0.00087

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "59.61"
    },
    "grouping_operation": {
      "using_filesort": false,
      "table": {
        "table_name": "cscart_product_prices",
        "access_type": "range",
        "possible_keys": [
          "usergroup",
          "product_id",
          "lower_limit",
          "usergroup_id"
        ],
        "key": "product_id",
        "used_key_parts": [
          "product_id"
        ],
        "key_length": "3",
        "rows_examined_per_scan": 88,
        "rows_produced_per_join": 17,
        "filtered": "19.97",
        "index_condition": "(`cscartdevel`.`cscart_product_prices`.`product_id` in (2127,2305,1812,2038,2306,2129,2171,2039,2040,1985,2114,2344,1949,2041,2318,1961,2042,1986,2343,2077,2172,2185,2159,2216,2218,2229,2228,2186,2184,1934,2358,1994,2006,2075,1962,2065,1992,2008,1984,1993,1936,2238,2237,2311,2298,2043,1954,1953,1752,1827,1870,1803,1828,1754,1770,1879,1874,1829,1864,1904,1842,1781,1894,2153,1886,1887,2085,2195,2130,2382,2011,1919,1922,1942,1923,1933,1945,1946,2376,1746))",
        "cost_info": {
          "read_cost": "57.85",
          "eval_cost": "1.76",
          "prefix_cost": "59.61",
          "data_read_per_join": "421"
        },
        "used_columns": [
          "product_id",
          "price",
          "percentage_discount",
          "lower_limit",
          "usergroup_id"
        ],
        "attached_condition": "((`cscartdevel`.`cscart_product_prices`.`lower_limit` = 1) and (`cscartdevel`.`cscart_product_prices`.`usergroup_id` in (0,1)))"
      }
    }
  }
}