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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b4f3075c9586470d93448f3f65720882b997edbbe8b0be1ab0df1d78dae625c' 
  AND token = 'u1Ecy7s1LaMBPkfcWyBlq5QN0wIR6PRZWqDfJ+D3D8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}