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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf0918cdda1182ab3adb5573d1f38814e9d90e345b0f9b1f51e288e1fdeff332' 
  AND token = 'XMxtpZLyEosWlTx/HAU3zp1G1uX6PT1NSRrm5jt0hKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}