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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b57ac406bb3f51e8281622adc594bce43b232820024c60e8f54373b8122967b2' 
  AND token = 'AtR9Kx0rvDGUua/s9BH+ngSwfaENL3qy2rLFcWTHiBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}