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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74170289f17316b8bada7b4659180db579456dd0f3c91cab9f1440e28df562a8' 
  AND token = 'Nv4+cLcZnB6Q9wn4oWPLJtWb/xmi32blJdNAMhdadD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}