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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a6a62c11b504f0b197f87ec85839bc156fb0c123905b095d0f77f83f489d4c8' 
  AND token = 'OqK8UvvXDJDZDeifSqe+iODZ3T3aJMOQ1qcH88FlAko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}