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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9269b53026c464b57994bddbe44862671a6f8147c7459c046f8668f171fd07f8' 
  AND token = 'WDumjFASL6t4bjfxFzpBlnht/ufZcRyhBNUHzrRj71U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}