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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3cf02aa03b922b42ebb6a949158873242a07fc03ac37f1b8ece15e47eb867ec' 
  AND token = 'L2mkD1lxJ+cWVXxxN4kqFFtUqVwfgDa3ZfM5E0/vygk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}