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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e31220dcca4bdd26a5196169f4f93e088b06bb5e520ad9834d62bca765c26f33' 
  AND token = 'ERQ3Lia9iKrrcs7hXx0xmsSWK+++rtoPCgIht0jxnQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}