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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87a8218b1b4a81146a4ee491b5d612009a07e3522e78c1d31c6efd79fef534eb' 
  AND token = 'AcnvkXH+i1Eb24l6BKB4zXcrEbenxmiRzqS0WJcquaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}