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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d385b36436b64e7fab1cda6190d838f2a434430a8c6421b4fb282e91a061a8b' 
  AND token = '+eqyXNF8CZR4wzGabbD4nnHL8GxQKNVF2gN16lDq+HY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}