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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dfcf19dd87e588310cc13bc086c77848659a4af9272c50dab1555d461150b98' 
  AND token = 'EFX35kOyVHXoLY+IoAeXAxdcZcS7Dr3BBtAj1tAkNag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}