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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff8056e49aeefc55c264d0d630f6864605e8b7711c0bfc9f1b8649438d0c67a8' 
  AND token = 'b3+8u+OHT8vkJTAD1JdwCl8AUOGn/l2xlvKoJRUGk2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}