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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186d3ffa90842ee33a9089a6a41b7dc2f8bcbf822ef50ccc674cae96b670374f' 
  AND token = 'lpROi/BSxD986KiH6M3pcMKRakG0m5tA0rUGDXvyj7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}