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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2d2a9ac7bba3d715c81735f5376a4e6150def1b995f0e9d7f616f37f1e3901a' 
  AND token = '0QcCHRnGSWliFkiB7dAePNQb4fqX+SUoHlOl1ON73mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}