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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c61a4dc80c6edf55489443fbc54019ccc4f0381e6904f4fb94504b1c8699f154' 
  AND token = 'cGZaZtt2wQIgAuiTV+GrRozvMgFCF82IDHFIr4LIQ4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}