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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7ce2ce1a38db34686c5775ca1b9ab0891d35fb4739535b633b063e2cbb96b53' 
  AND token = 'Y69AMJWBgUpVC4gpgVB0T+t0uinxhEg25l4n3ihyDyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}