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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ab47891be2c89b2847ce95e8e767904b59fcd80ffd111da568b9bed3d7aaf4' 
  AND token = '/5EmAK6w6tKdvj5eGcX1kh0JnvJXc852F5F+U0gvlw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}