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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edd540b058417b2cd5566f18fcc010ca308ecc842eadaf4962648b6cdab3c3cb' 
  AND token = 'Or06QFly8CDzoDx+i/WzuiarGAIt9jIkK7y8hNhxjro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}