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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f04b7c93a78231b2cfe540f3740675c47fa1d449bde08e3781a348ab117c0b97' 
  AND token = 'KxDAAbH1Kz0ru2eiKnRnsBTOR2QUlHJtm+23HoKHJ3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}