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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b54aa2c3695d0e81ea55e49380b2891db0a4215b36354bbe665c1b0ba21e3f49' 
  AND token = 'fzWa20LEIG4VAssr0qzX5npKKeFtDZ+pndd5HzCTxX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}